On research into the causes of cancer cell metastasis
The cells with which cancer spreads throughout the patient's body have distinctive molecular features. Knowledge of these features makes it possible to transform malignant cells into benign ones.
If there were no metastases, surgical removal of the tumor would be enough to cure the cancer. However, as a rule, when it is possible to detect a "primary" tumor, some of the cells have already left it and settled in other organs, like the seeds of a "secondary" cancer. In the further struggle against malignant degeneration, it is very rare to win.
If it were possible to control the formation of metastases, cancer would not be such a formidable disease. Fortunately, the study of metastasis is developing very rapidly. Fifteen years ago, when our research began at the Weizmann Institute in Israel, it was already clear that some tumors metastasize to a greater extent than others. It was also clear that in any given tumor, the cells differ in their ability to form metastases: some cells metastasize much more efficiently. These facts served as the basis for research in which we demonstrated that metastatic cells differ from non-metastatic cells in a number of ways.
Our data helps us understand how cells form metastases and how this can be prevented. Recently, based on the results of our research, we have achieved successful immunization against lung cancer metastases in mice. Such experiments can serve as a basis for the development of an "anti-cancer vaccine."
Of course, there is still a lot to be done. The properties of metastatic cells have not been fully studied. In addition, it is still unclear to what extent our data obtained in experiments on mice are applicable to human treatment. We are also investigating the relationship between the formation of metastases and the action of oncogenes (genes whose activation leads to the development of cancer), since it is unknown whether these genes, which determine uncontrolled growth, are responsible for the spread of cancer. We hope that our research will also help to find answers to a number of related questions: why do some tumors metastasize more strongly and others less, why do brain tumors not metastasize, although tumors of other organs metastasize to the brain. Actually, our work is only a part of extensive ongoing research aimed at establishing the molecular basis of malignant degeneration.
To establish the ability of individual cells to form metastases, they isolated cells from the primary tumor and grew a clone from each cell individually. (All cells in the cloned population are identical because they are descendants of the same cell.) Join 1xBet with the 1xbet promo code a 100% welcome bonus of up to BDT 15600 for Bangladesh players. 1xBet offers one of the most unique bookmaker bonuses you will ever see, with a bonus for a series of losing bets. This promo allows you to earn bonus bets if you are on a bad losing streak.
If there were no metastases, surgical removal of the tumor would be enough to cure the cancer. However, as a rule, when it is possible to detect a "primary" tumor, some of the cells have already left it and settled in other organs, like the seeds of a "secondary" cancer. In the further struggle against malignant degeneration, it is very rare to win.
If it were possible to control the formation of metastases, cancer would not be such a formidable disease. Fortunately, the study of metastasis is developing very rapidly. Fifteen years ago, when our research began at the Weizmann Institute in Israel, it was already clear that some tumors metastasize to a greater extent than others. It was also clear that in any given tumor, the cells differ in their ability to form metastases: some cells metastasize much more efficiently. These facts served as the basis for research in which we demonstrated that metastatic cells differ from non-metastatic cells in a number of ways.
Our data helps us understand how cells form metastases and how this can be prevented. Recently, based on the results of our research, we have achieved successful immunization against lung cancer metastases in mice. Such experiments can serve as a basis for the development of an "anti-cancer vaccine."
Of course, there is still a lot to be done. The properties of metastatic cells have not been fully studied. In addition, it is still unclear to what extent our data obtained in experiments on mice are applicable to human treatment. We are also investigating the relationship between the formation of metastases and the action of oncogenes (genes whose activation leads to the development of cancer), since it is unknown whether these genes, which determine uncontrolled growth, are responsible for the spread of cancer. We hope that our research will also help to find answers to a number of related questions: why do some tumors metastasize more strongly and others less, why do brain tumors not metastasize, although tumors of other organs metastasize to the brain. Actually, our work is only a part of extensive ongoing research aimed at establishing the molecular basis of malignant degeneration.
To establish the ability of individual cells to form metastases, they isolated cells from the primary tumor and grew a clone from each cell individually. (All cells in the cloned population are identical because they are descendants of the same cell.) Join 1xBet with the 1xbet promo code a 100% welcome bonus of up to BDT 15600 for Bangladesh players. 1xBet offers one of the most unique bookmaker bonuses you will ever see, with a bonus for a series of losing bets. This promo allows you to earn bonus bets if you are on a bad losing streak.
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